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8-night Upper Mississippi River Cruise

St. Louis/St. Paul
8-night Upper Mississippi River Cruise
August 21, 2026
American Cruise Lines: American Serenade
St. Louis/St. Paul
Vacation Offer ID 1560767
Reference this number when contacting our travel specialist.
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Exclusive Offer
  • $100 per Couple Shipboard Credit
Overview
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Ship Info
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Staterooms
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Deckplans
The Signature Collection – Exclusive Amenities
The Signature Collection Sailings offer Exceptional Value and Exclusive Amenities.

Cruise Inclusions

  • Cruise
  • Meals
  • Entertainment and more
  • Destination Guide
  • Suggested Shore Excursions
Destination Arrival Departure
St. Louis

St. Louis 08/21/2026

Tucked away beneath the majestic limestone bluffs lies the charming port of Alton, Illinois, serving as a gateway to endless adventures in St. Louis and beyond. But before you set off on your escapades, start your journey with a visit to the captivating National Great Rivers Museum. Learn about the fascinating tales of the upper Mississippi River, exploring its extensive history, the communities it sustains, and the diverse ecosystems it nurtures.
08/21/2026 08/21/2026
St. Louis (Alton)
08/21/2026 08/21/2026
Mississippi River Cruising
08/22/2026 08/22/2026
Hannibal
08/23/2026 08/23/2026
At Sea
08/24/2026 08/24/2026
Muscatine
08/25/2026 08/25/2026
Dubuque
08/26/2026 08/26/2026
Winona
08/27/2026 08/27/2026
Red Wing
08/28/2026 08/28/2026
St. Paul
08/29/2026 08/29/2026
American Cruise Lines: American Serenade
American Serenade won Cruise Critic’s Editors’ Picks Award for Best New River Cruise Ship of the Year recently, the first time an American ship has received this prestigious award. Introduces an updated modern interior design, integrating an elegant and refined aesthetic with tradition for the spacious comfort found aboard all of ships Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.
Ship Highlights
  • Ship features an on board fitness center and many spacious lounges where you can relax after the day’s adventures
  • Relax and unwind at Sundeck with beautiful views passing by
  • The Ship showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship
Ship Statistics
Maiden Voyage
2023
Passenger Capacity
175
Number of Staterooms
91
Number of Suites
16
Wheelchair Accessible
Yes

Suite

Veranda Suite (Private Balcony) (VS) Call for pricing
Veranda Suite (Private Balcony)
  • Category: VS
  • Deck 4
With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.
Grand Suite (Private Balcony) (GS) Call for pricing
Grand Suite (Private Balcony)
  • Category: GS
  • Deck 4
The luxurious Grand Suite measures 650 sq. ft. and offers panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a private balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.

Balcony

Single (Private Balcony) (SGB) Call for pricing
Single (Private Balcony)
  • Category: SGB
  • Deck 4
  • Deck 3
  • Deck 2
Perfect for the solo traveler, the Single staterooms offer all of the amenities you expect from a fine hotel. At 250 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.
Balcony Stateroom (AAR) Call for pricing
Balcony Stateroom
  • Category: AAR
  • Deck 1
AAR staterooms on the main deck offer complete comfort with approximately 275 sq. ft. of living space. Enjoy a full-size bathroom, large picture window, and door leading out to a furnished private balcony. These staterooms also feature a large sitting area, ideal for getting together with friends.
Balcony Stateroom (AAM) Call for pricing
Balcony Stateroom
  • Category: AAM
  • Deck 3
Located on the third deck, these spacious staterooms feature commanding views of the passing river landscapes. At 350 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor-to-ceiling sliding glass doors with a private balcony to offer panoramic views from every angle.
Balcony Stateroom (AAC) Call for pricing
Balcony Stateroom
  • Category: AAC
  • Deck 2
AAC staterooms are conveniently located on the second deck and offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular views of the surrounding landscape. At 316 sq. ft., these staterooms also offer a sitting area, desk and full-size bathrooms.
Fares listed are per person, based on double occupancy and include all gratuities, port charges and fees.
Prices are per person based on double occupancy. Pricing on some sailings may reflect special limited time offers, not combinable with any other offers/discounts. Valid on new bookings only. American Cruise Lines includes all shipboard meals, entertainment, tips and gratuities, alcohol, and other port charges and fees in the price of the cruise. Many shore excursions are also included in the cost of the cruise.

All fares are quoted in US Dollars.

Deck 5

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 4

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 3

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 2

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 1

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)